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spectral-domain structural oct with enhanced depth imaging (edi) heidelberg spectralis hr2 + oct  (heidelberg engineering)

 
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    heidelberg engineering spectral-domain structural oct with enhanced depth imaging (edi) heidelberg spectralis hr2 + oct
    Spectral Domain Structural Oct With Enhanced Depth Imaging (Edi) Heidelberg Spectralis Hr2 + Oct, supplied by heidelberg engineering, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/spectral-domain structural oct with enhanced depth imaging (edi) heidelberg spectralis hr2 + oct/product/heidelberg engineering
    Average 90 stars, based on 1 article reviews
    spectral-domain structural oct with enhanced depth imaging (edi) heidelberg spectralis hr2 + oct - by Bioz Stars, 2026-04
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    <t>Longitudinal</t> <t>Imaris</t> cell counts in MDA-MB-231 aggregates before and after 12h SL treatment at respective IC 50 doses, presented alongside dissociated counts from the same aggregates. The number of cells present decreases for both 2.5D and 3D aggregates after 12h treatment with DLSL (1A,C) and SL-EE-D (2A,C). Dissociated cell suspensions obtained from the same aggregates post-imaging and stained with trypan blue revealed a large proportion of necrotic cells (1B,D and 2B,D). Untreated MDA-MB-231 <t>OCT</t> aggregate data (3A,C) shows no decrease in cell count over the 12h period, while trypan blue staining registered necrotic cells within the models (3B,D). This necrosis is likely due to a lack of media and oxygen diffusion into the center of the aggregate, and is more pronounced in 3D aggregates.
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    <t>Longitudinal</t> <t>Imaris</t> cell counts in MDA-MB-231 aggregates before and after 12h SL treatment at respective IC 50 doses, presented alongside dissociated counts from the same aggregates. The number of cells present decreases for both 2.5D and 3D aggregates after 12h treatment with DLSL (1A,C) and SL-EE-D (2A,C). Dissociated cell suspensions obtained from the same aggregates post-imaging and stained with trypan blue revealed a large proportion of necrotic cells (1B,D and 2B,D). Untreated MDA-MB-231 <t>OCT</t> aggregate data (3A,C) shows no decrease in cell count over the 12h period, while trypan blue staining registered necrotic cells within the models (3B,D). This necrosis is likely due to a lack of media and oxygen diffusion into the center of the aggregate, and is more pronounced in 3D aggregates.
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    Longitudinal Imaris cell counts in MDA-MB-231 aggregates before and after 12h SL treatment at respective IC 50 doses, presented alongside dissociated counts from the same aggregates. The number of cells present decreases for both 2.5D and 3D aggregates after 12h treatment with DLSL (1A,C) and SL-EE-D (2A,C). Dissociated cell suspensions obtained from the same aggregates post-imaging and stained with trypan blue revealed a large proportion of necrotic cells (1B,D and 2B,D). Untreated MDA-MB-231 OCT aggregate data (3A,C) shows no decrease in cell count over the 12h period, while trypan blue staining registered necrotic cells within the models (3B,D). This necrosis is likely due to a lack of media and oxygen diffusion into the center of the aggregate, and is more pronounced in 3D aggregates.

    Journal: bioRxiv

    Article Title: Sophorolipid Candidates Demonstrate Cytotoxic Efficacy Against 2D And 3D Breast Cancer Models

    doi: 10.1101/2022.09.01.506226

    Figure Lengend Snippet: Longitudinal Imaris cell counts in MDA-MB-231 aggregates before and after 12h SL treatment at respective IC 50 doses, presented alongside dissociated counts from the same aggregates. The number of cells present decreases for both 2.5D and 3D aggregates after 12h treatment with DLSL (1A,C) and SL-EE-D (2A,C). Dissociated cell suspensions obtained from the same aggregates post-imaging and stained with trypan blue revealed a large proportion of necrotic cells (1B,D and 2B,D). Untreated MDA-MB-231 OCT aggregate data (3A,C) shows no decrease in cell count over the 12h period, while trypan blue staining registered necrotic cells within the models (3B,D). This necrosis is likely due to a lack of media and oxygen diffusion into the center of the aggregate, and is more pronounced in 3D aggregates.

    Article Snippet: Aggregate morphology was characterized using Optical Coherence Tomography (OCT) structural imaging with Imaris analysis software, as previously described .

    Techniques: Imaging, Staining, Cell Counting, Diffusion-based Assay